Updated March 9, 2026
LangChain is the most widely adopted framework for building LLM-powered applications and AI agents. It provides abstractions for chains, agents, tools, memory, and retrieval that make it easy to compose complex AI systems. LangGraph, its agent orchestration layer, enables building stateful, multi-actor workflows with human-in-the-loop capabilities. LangSmith provides tracing, evaluation, and monitoring. The LangChain ecosystem is the largest in the AI application development space.
The OpenAI Agents SDK is a lightweight Python framework for building multi-agent workflows with built-in tracing and guardrails. It provides primitives for defining agents with instructions and tools, orchestrating handoffs between agents, and implementing input/output guardrails for safety.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
Pros
Cons
Pros
Cons
Choose LangChain if you wantChoose if you want
Choose OpenAI Agents if you wantChoose if you want
Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.